Do you have an upcoming product release or need to verify a vacuum sterilization method?

The Guided Wave Hydrogen Peroxide Vapor Monitor (HPVM), is a simple turnkey solution for the measurement of hydrogen peroxide and water (H₂O₂  and H₂O) concentrations in the vapor phase. Conveniently Guided Wave offers short term HPVM rental solutions which provide continuous, accurate data for documentation and validation requirements. The HPVM rental plan is a complete ready-to-go system and includes calibration certificate, 6-meter fiber optic cables, and a redesigned 50 cm pathlength G-SST probe. The analyzer operates in real-time, which takes the guesswork out of determining the H₂O₂ and H₂O concentrations during cycle development and throughout the actual vacuum sterilization cycle. 

Why Rent an Hydrogen Peroxide Vapor Monitor?

Renting an Hydrogen Peroxide Vapor Monitor (HPVM) is an ideal solution for short term monitoring needs. When only using an instrument for internment periods of time, it doesn’t make financial sense to invest precious resources learning how to set-up and operate a new interim system. As a result, the quick installation and start-up, along with the ease of operation and control, make the HPV Monitor a smart choice for rental applications.

The HPVM  is calibrated at the factory and no programming or modification is required by the user. To start-up, simply power on the HPV monitor, connect the G-SST probe via the fiber optic cables, and collect a ZERO or background reading in the dehumidified sterilization isolator. Immediately following an inject of sterilant, accurate H₂O₂ and H₂O concentration measurements may begin. This allows for easy operation and controlled monitoring during the sterilization process.

Why Use Spectroscopy to Monitor Sterilant Concentration?

Because the HPVM uses proven NIR spectroscopic technology for quantifying the concentration of vaporized hydrogen peroxide in the sterilization chamber, renters/users can be totally confident in the monitoring results. NIR Spectroscopy is the only real-time monitoring technology capable of operating inside of a vacuum chamber during the sterilization process. Electrochemical hydrogen peroxide sensors cannot handle the harsh vacuum conditions and elevated temperatures used in a modern sterilization process.  The HPV Monitor is not suitable to determine low (<100 ppm) concentrations, which are of occupational health and safety concerns.

The Smart Choice for Reliable Hydrogen Peroxide Vapor Measurement

Guided Wave’s HPV Monitor delivers accurate, real-time H₂O₂ and H₂O measurement results under vacuum conditions. Its long term stability and no maintenance requirements make it a cost-effective, smart choice to help optimize production and ensure product quality ultimately enhancing profitability. Quick and accurate determination of how much sterilant is actually in the vacuum chamber is achieved using the HPV Monitor.

An ISO 9001 certified company, Guided Wave maintains expert technical support and responsive global service for the lifetime of the HPV analyzer system.

Need a Long Term Sterilant Monitor?

Contact a Guided Wave Sales Representative to discuss purchasing the new Vaporization Hydrogen Peroxide Analyzer or the Vaporized Ethylene oxide (ETO) Analyzer. Based on the ClearView’s proven dual-beam photometer technology. the new HPV and ETO analyzers provide a cost effect monitor.

However, for diesel/gas oil applications it is highly recommended to use a heated MultiPurpose Flow Cell (MPFC) with a heated incoming line to dissolve the trace levels of water in the sample. While direct insertion probes eliminate sample loops and sample systems and their associated problems, sometimes it is necessary to install sample loops for safety, service, and/or sample conditioning reasons. The MPFC is a convenient, compact, rugged sample interface that is easy to install and even easier to service. The cell’s sapphire windows can be cleaned by simply removing a clean-out plug (a Guided Wave innovation) for direct access to the windows without disconnecting process lines or fiber optic cables.

How to Choose the Right Probe or Flow Cell for Refinery Measurements

Guided Wave probes and flow cells offer high throughput, collimated optical beams through the sample, yielding lower noise and more accurate transmission values free of sample index of refraction effects. For faster maintenance and cleaning of insertion probes, Guided Wave’s Extractor Mechanism can be used. The controlled extraction of an in-line probe from pressurized process streams or reactors can be accomplished without shutting down the process, allowing continued use of the analyzer to verify process quality. Coupled with a gate or ball valve, these extractors have proven safe and effective in a variety of refinery installations such as Reformer, Gasoline Blending, Blender and Feed Streams saving downtime. James Low, Guided Wave’s Director of Sales and Support states, “The SST insertion probe extractor assembly is worth every penny when you consider the time saved on insertion probe maintenance.” He continue “I’ve been with Guided Wave almost since its beginning and the SST probe and the multipurpose flow cell are extremely durable and reliable. Our probes and flow cells are compatible with nearly every brand of analyzer and in normal refinery use they function virtually forever”.

SMS provides an advantage over other systems. For example, with FT-NIR analyzers, validation is often done using external fluids (i.e., Pentane and Toluene) which may not be readily available and are an expensive consumable. With a Guided Wave NIR-O analyzer the SMS validation system is simple and requires no maintenance or consumables. Using SMS there is no need to interrupt the other channel operation. It provides automatic and continuous analyzer validation according to ASTM methodology.

The performance tests identified in the ASTM D-6122 validation practice are diagnostics that can be used to detect changes in analyzer performance. This validation provides assurance that the measurement produced by the analyzer is a result of equipment that is operating properly. Since this is a hands-off procedure, it can be conducted in the background with no human intervention. The validation is done with an internal filter having a characteristic spectral signature. There are no liquids or other external sampling modes that are necessary. Everything is contained inside the
NIR-O analyzer enclosure and all SMS related materials are completely non-hazardous. This topic is addressed in ASTM practice D-6122-19 under
instrument performance tests. The ASTM practice provides a set of criteria for establishing baseline analyzer performance validation. Three levels of hardware testing are established:
Level 0 – When Level 0 – Tests the analyzer hardware’s capability to generate a consistent spectrum. This is accomplished by measuring photometric noise, baseline stability, spectral resolution, photometric linearity, and wavelength stability.
Level A – Tests compare key parts of the spectral data with historical data to identify deviations.
Level B – Tests and monitors the instrument performance for deviations that affect the system calibration models.

Guided Wave’s SMS operation is seamlessly integrated into the OmniView control software for NIR-O. SMS provides assurance that all ASTM required measurements are conducted at the appropriate time and will send a signal or message to the control system if a validation issue is encountered. Learn more about SMS.

There are 2 Options for Adopting a NIR-O Spectrometer for Existing M412 Users:

ClearView db is a modular filter photometer suitable for many OEM applications. By selecting up to six filters ranging from 420nm to 2100nm each with a dedicated detector, system integrators have successfully utilized ClearView db for real-time monitoring of liquids and gasses. Examples include: acid & OH number monitoring, detection of copper in acid baths, hydrogen peroxide vapor sterilization, NO₂ gas sterilization, water content of solvent or gasses, or color. Additionally, the ClearView db can monitor up to 2 process locations using either flow cells or direct insertion probes.

Guided Wave provides OEM partners with a detailed MODBUS TCP/IP map and implementation examples. This data enables system integrators to quickly incorporate the ClearView db into their existing projects. MODBUS enables directional communication and remote operational control of the analyzer. Commands include: taking a reference, zero, or background scan; applying a slope and bias correction to the measurement result; and alarms or errors. For example, analyzer faults or off spec process alarms. ClearView db monitor does not require an external computer for configuration and operations, Modbus TCP/IP communication is completely integrated into the system and does not need extra software or hardware from a third party supplier

Ultimately by implementing the OEM ClearView db photometer with MODBUS, critical process monitoring information can be quickly delivered to process engineers and other end-users. Allowing your customers to make informed decisions in real-time.

Interested in learning more about the OEM process for the ClearView db?