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Vaporized Hydrogen Peroxide – Applications and Monitoring Solutions

Written by Terri Melle-Johnson on . Posted in Process Insights, Guided Wave. Leave a Comment

Vaporized Hydrogen Peroxide – Applications and Monitoring Solutions

Sterilizing medical instruments in autoclave

Vaporized Hydrogen Peroxide is one of the few sterilization methods that is effective for virus deactivation and microbial reduction. This blog post discusses various aspects of the sterilization market and the need for spectroscopic monitoring equipment for validating hardware and sterilization cycle design.

Reducing Nosocomial or Hospital-Acquired Infections, Miniaturizing Technology for Table-Top Office Sterilizers

The future of the sterilization market is in small semiportable sterilization isolators geared towards doctors’ offices and other front-line medical personnel. The driving force behind the adoption of this technology is the reduction of nosocomial or hospital-acquired infections. Medical equipment is routinely disinfected with alcohol between each patient, but that is not always enough to properly disinfect the instruments. By placing medical equipment, such as a stethoscope into a microwave sized chamber, medical staff can be assured that the item is properly sterilized. If a protocol is established to effectively and efficiently sterilize equipment after each patient is treated nosocomial infections will be reduced.

Using Spectroscopy to Compliment Rapid Biological Indicators

Biological indicators (BI) are the final go/no go of sterilization testing. By placing biological indicators in the sterilization chamber with the load (product to be sterilized), technicians can verify to regulatory standards that a kill dose of sterilant was received. Guided Wave’s HPV analyzer was developed to complement BI technology, by providing a real-time read-out of the sterilant concentration. If a biological indicator shows that a kill dose was not received the data produced by the Hydrogen Peroxide Vapor Analyzer can be used to help explain what went wrong with the sterilization cycle.  By combining biological indicators with spectroscopy, engineers designing the next generation of tabletop sterilizers can reduce the time to market for new products.

Benefits of Simultaneous Measurement of Water Vapor and Peroxide Vapor Concentration

A critical parameter during sterilization cycle development and validation of new sterilization hardware is that the product’s (item to be sterilized) surface is exposed for a minimum amount of time to the correct concentration of sterilant. In the case of vaporized hydrogen peroxide, one parameter to consider is the decomposition rate of hydrogen peroxide to water. By simultaneously measuring the water vapor and the hydrogen peroxide vapor, reaction kinetics can be determined.1 Spectroscopy is an accurate and reliable method to simultaneous determine water and hydrogen peroxide vapor.

The reaction kinetics (adsorption, absorption, and decomposition) of vaporized hydrogen peroxide (VHP) in a vacuum isolator will deviate from theoretical calculations as calculated by a mass balance equation.2 The Hydrogen Peroxide Vapor Analyzer uses near-infrared spectroscopy to measure the actual VHP and water vapor concentrations, corrections to reaction kinetics can be determined.  

If Hydrogen Peroxide and Water Vapor exceed the Relative Saturation (RS) where condensation occurs within the Sterilization Chamber, fouling of packaging of products being sterilized can occur.  Furthermore this condition usually violates the strict protocols associated with proper elimination of the bio-load. While the G-SST probe is water resistant when installed properly, the probe may not function optimally during condensation conditions. Actually the probe may become a good predictor should RS max be exceeded and a condensation fog exist.

According to the scientific study by Corveleyn3 spectrally gaseous Water (H2O) has near-infrared absorbance peaks located at 1364 nm, 1378 nm, and 1400 nm. Whereas Hydrogen Peroxide Vapor (H2O2) was determined to have an absorbance peak located at 1420 nm. By selecting these wavelengths with the corresponding baseline corrections. The Hydrogen Peroxide Vapor Analyzer is factory calibrated to account for the interference. 

Why use Vacuum Sterilization?

Creating a vacuum is a critical part of many low temperature hydrogen peroxide sterilization systems. By pulling a vacuum inside of the sterilization chamber the air and other contaminants are removed. This prevents the air and contaminates from breaking down the hydrogen peroxide vapor prior to it reacting with the bacteria. Additionally, the vacuum enables hydrogen peroxide to be pulsed into the chamber and therefore helps drive the sterilant gas into the packaging material. The vacuum also increases the effectiveness of any aeration at the end of the cycle to neutralize residual sterilant.

Low temperature vacuum sterilization is ideal for sensitive products and BioPharma substances such as those that are protein based. The modern basis for gently handling sensitive products utilizes multiple sterilant pulses with a soak or dwell time before evacuating the chamber. The process of pulsing sterilant into the chamber prior to evacuation can be repeated several times to achieve a proper sterlization levels. This modern approach to vacuum sterlization eliminates the Bio-Burden associated with the products themselves. 

Benefits of NIR Monitoring of Atmospheric and Low Temperature Vacuum Sterilization

The Guided Wave Vapor Probe connected to the near-infrared beam of a Hydrogen Peroxide Monitor is invariant to the pressure or velocity of the gas in the probe’s measurement zone. The vapor probe directly measures the number of molecules of H2O2 and H2O that exist in its beam at any particular moment. This real-time measurement is regardless of pressure changes due to injection or pulses of sterilant, chamber pump down, or chamber aeration. NIR is a remarkable measurement approach for Atmospheric and Low Temperature Vacuum Sterilization. Real-Time Data is generated throughout the sterilization cycle(s) and the output is sent to data logs every few seconds, providing a valuable Audit Trail for Cross Validation of System Performance. 

Monitoring the Vaporized Hydrogen Peroxide Concentration in Walk-in Vacuum Sterilization Isolators

Walk-in sterilization systems are used for high volume sterilization. Carts or mobile racks of the product can be loaded into and out of the isolation chamber to ensure high throughput. To ensure that proper mixing is achieved several G-SST probes can be placed in the isolation chamber. The data generated by the multiple probes provides a profile gradient that can be monitored during the sterilization process. Determining the sterilant gradient inside of a reaction chamber is an important step in validating the design of the chamber.

Bio-safety Room Decontamination and Virus Deactivation

Similar to isolators, BioSafety labs are large rooms used for biological experiments. Due to the nature of the research conducted, these rooms require periodic decontamination and virus deactivation. The National Cancer Institute (NIH) Research and Production Center at Ft. Detrick, Maryland uses vaporized hydrogen peroxide to decontaminate whole areas and rooms. The NIH facility uses spectroscopy to monitor sterilant levels in hard to access locations. Mounting a G-SST probe instead of a biological indicator in these locations saves time and increases technician safety. Learn more about this customer success story.

References

  1. https://pdfs.semanticscholar.org/9171/1c2b3ab32a797ac259598be912023a413549.pdf
  2. Brown, et al., “Calibration of Near-Infrared (NIR) H2O2 Vapor Monitor,” Pharm. Eng. 18, (6), 66–76, (1998)
  3. Corveleyn, S., Vandenbossche, G.M.R. & Remon, J.P. Near-Infrared (NIR) Monitoring of H2O2 Vapor Concentration During Vapor Hydrogen Peroxide (VHP) Sterilisation. Pharm Res14, 294–298 (1997). https://doi.org/10.1023/A:1012085702372

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What are you Measuring? When to know if Process Spectroscopy is the Measurement Technology you should use.

Written by Terri Melle-Johnson on . Posted in Process Insights, Guided Wave. Leave a Comment

When to know if Process Spectroscopy is the  Technology you need for Liquid, Vapor or Gas Measurements?

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Use this flowchart to figure out if process spectroscopy is the best measurement technology for your application.  If you reach the purble box (I don’t know) in this flowchart you can complete the Application Questionnaire and the experts at Guided Wave will help you. There is also more information on the how to select an analyzer page. Want to send us a question? Use the contact us button below.

When to Know if Process Spectroscopy is the Technology for Liquid, Gas or Vapor Measurements

Which Process Spectroscopy Analyzer did you Choose?

Select the product name below for more information about each of these Guided Wave and ANALECT analyzers: 

Flowchart

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Canadian Registration Number (CRN) Certified Probes for Process Spectroscopy

Written by Jayne W on . Posted in Process Insights, Guided Wave. Leave a Comment

Canadian Registration Number (CRN) Certified Probes for Process Spectroscopy

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A Canadian Registration Number (CRN) is a number issued to the design of a pressure vessel or fitting by each province or territory of Canada. The CRN identifies the design has been accepted and registered for safe installation and use. As of October 2019, Guided Wave has submitted more than 3,500 different design configurations for our probes and flow cells to be CRN certified.

CRN certified probes and flow cells are engineered by Guided Wave to meet the strict safety and application requirements for the Canadian petrochemical, refining, and polymer markets. By coupling these probes with certified (CSA, ATEX, IECEX) process analyzers, Guided Wave can offer complete process monitoring solutions to Canadian customers. We currently have CRN registered designs for Ontario, Alberta, and Quebec. However, complete process monitoring solutions for all provinces can be implemented – contact us for more information.

All CRN probe sales include hydrotest and x-ray test results.

Gold Braze Single-Sided Transmission Probe and Gear Driven Extractor

NIR-Infrared spectroscopy with both DG-NIR and FT-NIR is now possible with the family of CRN certified in situ transmission probe and extractor.

CRN Probe Features

  • Corrosion resistant construction
  • Rugged and vibration resistant design
  • Sealed against ambient moisture infiltration
  • High optical throughput for low noise spectroscopy
  • Temperatures to 300 °C
  • Pressures to 2000 psi or 138 bar
  • Higher pressures are available on request

Optional CRN Certified Accessories

The Single-Sided Transmission probe is available with an Extractor Assembly under a single CRN. This extractor accessory allows for a CRN probe to be easily adapted to different kinds of process installations. Additionally, the Extractor Assembly allows for quick and easy removal and servicing of probes, and avoids costly shutdowns by allowing the process to continue while the probe is offline. The standard flange on the extractor enables it to be installed into common process pipe configurations.

Certified Probes for High Pressure and Temperature Applications

The family of Heavy Duty probes are a special class of SST probes designed to withstand up to 2400 psi. The Heavy Duty probes can be constructed in 304, 304L, 316, 316L, and Hastelloy, with up to a 50 mm path length. 

CRN Certified Flow Cells for NIR Spectroscopy

Guided Wave’s family of 1, 2, 5, 10, and 20 mm pathlength flow cells are hydro-tested to demonstrate operation at 8100 pounds of pressure. This high safety factor has enabled Guided Wave to seek CRN certification for the flow cells in Ontario, Alberta, and Quebec.

Simple, Serviceable Flow Cell Design

Key elements of the CRN Certified flow cell (MPFC) design are simple, serviceable o-ring seals, the clean-out port, high optical efficiency, slip jointed conduit-ready connections, sapphire windows, a clean flow pattern, and o-ring sealed optics to prevent ambient moisture infiltration. The flow cell probe can be field disassembled for o-ring service and reassembled without changing the optical pathlength, a crucial parameter for repeatable measurements. The multi-purpose flow cell now boasts a dual seal at the sapphire “window-to-process” interface. This doubles protection for the expensive internal optical lenses.

Operating Range of CRN Flow Cell

The certified Multi-Purpose Flow Cell operates over the following pressure and temperature ranges:

  • Temperatures to 300 °C (o-ring material dependent)
  • Pressures to 1000 psi (o-ring durometer dependent)
  • Available in five standard pathlengths 1, 2, 5, 10, and 20 mm

CRN Certified Probes Compatible with Bruker and ABB Spectrometers

The CRN Certified probes and flow cells are manufactured by Guided Wave to facilitate full integration with any fiber-optic spectrometer manufacturer. The family of CRN certified devices are fully compatible with the Matrix-F FT-NIR analyzer, ABB’s full line of FT-NIR spectrometers, and AIT’s optical analyzers. The market-leading optical efficiency of our sample interfaces will improve the optical performance any spectrometer when connected with 400 to 600 micron fiber optical cables and SMA 905 or FC connectors.

Need Help Purchasing a CRN Certified Spectroscopy Probe or Flow cell?

Contact a Guided Wave sales representative to determine the best CRN Certified configuration for a process sample interface.

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Announcing direct integration of EigenVector’s SOLO Predictor with Omniview V2.0 software

Written by Jayne W on . Posted in Process Insights, Guided Wave. Leave a Comment

Announcing direct integration of EigenVector’s SOLO Predictor with Omniview V2.0 software

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Eigenvector Research and Guided Wave have partnered to implement an API between the Omniview V2.0 software and Solo_Predictor. This enables NIR-O Full Spectrum Analyzer users who develop models using Eigenvector’s MATLAB® based PLS_Toolbox or stand-alone Solo to use the real-time prediction engine, Solo_Predictor. Contact Guided Wave or your local representative to access this free of charge software update.

Steps to for Existing NIR-O Users to Implement Solo_Predictor

Time needed: 15 minutes.

Steps to integrate Solo_Predictor and Omniview Software.

  1. Provide proof of runtime license for the Solo_Predictor program
  2. Download software update from Guided Wave onto built-in analyzer PC

    A zip file containing updated python scripts and a 64-bit Solo_Predictor version 4.0.4 installation executable will be provided by sharepoint or drop box.

  3. Follow the installation procedure

    The installation procedure for existing users, requires moving some files into place.

Purchasing a NIR-O and want SOLO_Predictor to be preinstalled?

Existing EigenVector customers just need to provide proof of the run-time license when placing their order with Guided Wave. This will allow our production staff to implement the API on the analyzer computer.

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What’s a Photometer filter kit and how can it help me save money?

Written by Terri Melle-Johnson on . Posted in Process Insights, Guided Wave. Leave a Comment

What’s a Photometer filter kit and how can it help me save money?

Solid state filters are used in the ClearView db analyzer. The apparent color change represents different wavelength ranges. These filter are installed inside of the filter wheel in the ClearView db Analyzer

The ClearView db process analyzer is a photometer-based sensor platform. Before shipment, each platform is configured in Guided Wave’s factory to monitor specific conditions or applications specified by the end-user. The Clearview db provides a cost savings alternative to purchasing a process grade spectrometer. The cost savings are achieved by selecting (at the time of purchase) up to six filters, which are part of the analyzer’s hardware.

Each filter is chosen based upon the compounds to be measured. Every filter allows a ~10nm wide wavelength band of the analyzer light to reach the detector. All other light is essentially blocked by the filter. These filters are then installed inside the ClearView db, locking in the hardware portion of the calibration (The wavelengths that are measured). The software calibration is typically done in Microsoft Excel by the factory and converts the intensity of light for each filter/wavelength into the predicted answer.

The ClearView db delivered to the end-user is essentially customized for their specific purpose. The end-user may later modify the software portion of the calibration to adapt the analyzer for other requirements. For example, an offset or slope correction can be added to fine-tune the calibration based on data after installation at the customer site.

How Guided Wave Selects Filters?

Guided Wave has developed filter kits for many applications. For new applications, samples must be collected and scanned with a spectrometer (400-2100nm). Wavelength ranges that correlate well with the chemical changes are identified and compared against our stock of available filers for the closest match.

Each filter allows a narrow range of wavelength to be transmitted to the photometer detector. This is typically referred to as the bandwidth of the filter. Above are 4 proven photometer applications by wavelength represented by the red, gray, blue and yellow dots. By measuring these wavelengths we can monitor the specific application at a reduced cost in comparison to a full spectrum analyzer.  

If Guided Wave does not have a corresponding filter, a custom filter can be ordered from our vendor and added to our inventory to meet application demands.

The Anatomy of the ClearView db Analyzer

The photometer both transmits the source light and quantifies the light that was not absorbed by the sample. Optical grade fiber cablesare used to carry the light from the photometer to the sample and back. Using high-performance fiber cables permits the sample interface to be located up to 100 meters from the photometer.

The ClearView db can be divided into four major sections 

1) Electronics (Detector PCA):  the desired (analog inputs and outputs, Modbus interface, and Human Interface Display (touch screen)

2) Lamp Housing:  area of the light source.

3) Optical Multiplexor: (MUX): which programmatically switches between the reference and sample fiber optic cables. The reference fiber is our Dual Beam (db). It allows for automated corrections due to instrument noise and improves performance.

4) Detector Housing:  area where the filters and detectors are installed by Guided Wave at the factory (the graphic below shows 2 of the 6 possible filters).

ClearView db Photometer -Filter

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Alphabet Soup or Calibration Acronyms PART II

Written by Jayne W on . Posted in Process Insights, Guided Wave. Leave a Comment

Alphabet Soup or Calibration Acronyms PART II

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As the field of process spectroscopy grows, so does the number of acronyms associated with the measurement methods. In the last blog post, we discussed the acronyms related to calibration that users may encounter. This blog will give a brief overview of some acronyms that are in frequent use related to Guided Wave analyzers and products. Some of these are specific to Guided Wave, while others are related to the methodology as a whole. The list below is in alphabetical order.

ANSI – American National Standards Institute
The ANSI is a private nonprofit organization that oversees the development of voluntary consensus standards for products, services, processes, systems, and personnel in the United States. The organization also coordinates U.S. standards with international standards so that American products can be used worldwide. These standards ensure that the characteristics and performance of products are consistent, that people use the same definitions and terms, and that products are tested the same way.

ASTM – American Society for Testing and Materials
ASTM International is one of the largest voluntary standards development organizations in the world. They are a source for technical standards for materials, products, systems, and services. ASTM International standards have an important role in the information infrastructure that guides design, manufacturing and trade in the global economy.

ATEX
The European directive 94/9/EC requires that employers must protect employees from explosion risk in areas with explosive atmospheres. Manufacturers and importers must ensure that their products meet specific safety requirements. The goal of ATEX, which gets its name from the directive’s French title Appareils destinés á être utilisés en ATmosphères Explosibles, is to allow free trade of “ATEX” approved equipment within the EU by removing the need for separate testing and documentation for each member state.

CENELEC
CENELEC is the European Committee for Electrotechnical Standardization. This is a non-profit technical organization set up under Belgian law and composed of the National Electrotechnical Committees of 30 European countries. CENELEC’s mission is to prepare voluntary electrotechnical standards that help develop the Single European Market/European Economic Area for electrical and electronic goods and services removing barriers to trade, creating new markets and cutting compliance costs.

FT-NIR
Fourier transform spectroscopy is a measurement technique whereby spectra are collected based on time-domain measurements of the electromagnetic radiation. It can be applied to a variety of types of spectroscopy, including Near-Infrared spectroscopy (see NIR below).

ISO
ISO is an international-standard-setting body composed of representatives from various national standards organizations. The organization promulgates world-wide proprietary industrial and commercial standards. ISO is a network of the national standards institutes of 157 countries, one member per country, with a Central Secretariat in Geneva, Switzerland, that coordinates the system.

NIR
Near-Infrared or NIR is a region of the electromagnetic spectrum from about 750nm to 2600nm. Near Infrared Spectroscopy is the technique of using a sample’s NIR absorbance characteristics to predict parameters of interest. Molecules containing C-H, O-H, and N-H bonds absorb NIR radiation in specific regions or at specific wavelengths. These absorbance’s can then be used in a qualitative or quantitative measurement. NIR spectroscopy is widely used in both process and laboratory measurements across many industries (chemical, refining, pharmaceutical, polymer, semi- conductor, agricultural).

NIST
The National Institute of Standards and Technology (NIST), previously known as the National Bureau of Standards (NBS), is a non-regulatory agency of the United States Department of Commerce. The institute’s mission is to promote U.S. innovation and industrial competitiveness by advancing measurement science, standards, and technology in ways that enhance economic security and improve quality of life.

PAT
Process Analytical Technology (PAT) has been defined by the United States Food and Drug Administration (FDA) as a mechanism to design, analyze, and control pharmaceutical manufacturing processes through the measurement of critical process parameters and quality attributes. While this term was initially defined in relation to the pharmaceutical industry, the concepts and methods can be extended to other industries.

SST
The Single-Sided Transmission (SST) Probe is a rugged and reliable sample probe that is ideal for continuous process monitoring applications. SST means that light passes through the sample region only once. In contrast, transflectance probes pass twice, being reflected from the far end. The SST probe can be easily installed in a pipe or reactor through a single access port and works with any Guided Wave single-fiber spectrometer or photometer. Optional accessories make it easy to adapt the SST Probe to different kinds of process installations.

UV/VIS
UV/VIS spectroscopy is the measurement of the wavelength and intensity of absorption of ultraviolet and visible light by a sample. Ultraviolet and visible light are energetic enough to promote outer electrons to higher energy levels. UV/VIS spectroscopy is usually applied to molecules and inorganic ions or complexes in solution. The spectra have broad features that are of limited use for sample identification but are very useful for quantitative measurements. The concentration of an analyte in solution can be determined by measuring the absorbance at some wavelength and applying the Beer-Lambert Law.

Calibration Acronyms

ANSI- American National Standards Institute
ASTM- American Society for Testing and Materials
ATEX- Atmosphéres Explosibles (French)
CENELEC- European Committee for Electrotechnical Standardization
CIE – International Commission on Illumination
FT- NIR- Fourier Transform Near-infrared
ISO- International Organization for Standardization
NIR – Near-Infrared
NIST- National Institute of Standards and Technology
PAT- Process Analytical Technology
SST- Single Sided Transmission Probe
UV/VIS- Ultraviolet / Visible

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35 Year Anniversary!

Written by Jayne W on . Posted in Process Insights, Guided Wave. Leave a Comment

35 Year Anniversary!

From 1983 to 2018 – Guided Wave a leading manufacturer of online process analytical systems is pleased to announce the 35th anniversary of continuous business operation. Established in 1983, Guided Wave was an industry pioneer when it delivered the first fiber optic-based Near Infrared (NIR) analyzers. Read our story of 35 years

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Writing Custom Python Scripts in OmniView Part II

Written by Terri Melle-Johnson on . Posted in Guided Wave, Process Insights. Leave a Comment

Writing Custom Python Scripts in OmniView Part II

Writing Custom Python Scripts in OmniView Part II

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In part I of Writing Custom Python Scripts in OmniView, we discussed setting up a basic python script and determine the absorbance value at a specific wavelength. As shown in our training videos we recommend customers use Unscrambler Prediction Engine to implement PLSR or PCA calibrations. We also have a video demonstrating how to turn on additional statistics, such as Mahalanobis Distance.

When additional statistics are turned on, instead of returning a single floating point value, the Unscrambler Prediction Engine will return a python dictionary or array of answers (predicted properties). If you are operating near zero, the calibration may return a negative result. In many applications the answer, such as the concentration of water in a solvent, the real world value can never be less than zero. Therefore you may want to add some logic to your python method script to overwrite negative values and set them to zero.

The code below can be added to your custom python method script. Please note the tab indentation. Proper spacing is important in python syntax.

answer = unscramble(au)

for key in answer.keys():
    if answer[key] < 0:
        answer[key] = 0

Interested in learning more? Check out the training videos we have on our youtube channel.

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How’s Your Engine Running?

Written by Ryan Lerud on . Posted in Guided Wave, Process Insights. Leave a Comment

Fuel Quality = Engine Performance

During the course of a diesel engine’s life it is the fuel that represents more than 70% of its operating cost. Therefore maintaining fuel quality is imperative.

GW’s new application note, Monitoring the Cloud Point of Diesel Fuel, demonstrates how NIR spectroscopy is a time and money saving alternative to traditional methods for monitoring the cloud point of a diesel fuel, which is the temperature below which wax forms giving the fuel a cloudy appearance. This parameter is an important property of the fuel since the presence of solidified waxes can clog filters and negatively impact engine performance. (By the way do you know who invented the Diesel Engine?) (Answer at the bottom)

Traditional laboratory methods for the measurement of cloud point are optical in nature but rely on cooling the fuel for the wax formation to occur. Guided Wave’s NIR instrumentation can measure compositional changes in the fuel that will be directly related to the wax formation and hence the cloud point. This means no waiting around for the wax to form; you get data within seconds with this powerful NIR method.

This application note illustrates how the measurement of cloud point of diesel fuel is made possible by using Guided Wave (GW) optical probes coupled to a near-infrared spectrometer with fiber optic cables. The GW NIR instruments can be applied either on-line for real-time, continuous process monitoring or simply as a faster and more efficient laboratory procedure. The end result of excellent fuel quality is maintained meaning better performing engines!

  1. Rudolf Christian Karl Diesel was a German inventor and mechanical engineer, famous for the invention of the Diesel engine. Wikipedia Born: March 18, 1858, Paris, France

Welcome to Guided Wave

Written by Terri Melle-Johnson on . Posted in Guided Wave, Process Insights. Leave a Comment

Welcome to Process Insights’ Family

PROCESS INSIGHTS ANNOUNCES ACQUISITION OF GUIDED WAVE INC.

Greensboro, NC – March 1, 2022.  ProcessProcess Insights_Guided Wave logo Insights, a Union Park Capital portfolio company, announced today that it has acquired Guided Wave Inc. (“Guided Wave”) from Singapore-based Advanced Holdings Ltd.  Guided Wave, based in Rancho Cordova, California will join Process Insights’ existing broad portfolio of premium brands and technologies for process analytics, monitoring and control including COSA Xentaur, Hygrocontrol, Alpha Omega Instruments, LAR Process Analysers, Tiger Optics, ATOM Instrument, Extrel CMS and MBW Calibration.

Founded in 1983, Guided Wave designs and manufactures complete analytical systems utilizing Near Infrared (“NIR”) and Ultraviolet/Visible (“UV-VIS”) spectroscopic technologies.  Guided Wave is the only process NIR company that provides a complete, optically matched NIR analytical system yielding the best throughput efficiency and long-term performance that exceed industry standards.  Guided Wave’s analytical systems are designed for continuous online process performance while providing real-time data of laboratory quality in harsh, hazardous, and demanding environments.  Guided Wave’s products and technologies are used in a wide range of applications across a multitude of markets and industries including chemicals, petrochemicals, semiconductor, pharmaceuticals, biotechnology, and healthcare (sterilization and virus deactivation).

“For more than 35 years, Guided Wave has served a variety of customers and industries worldwide with leading spectroscopic process analyzer solutions.  With our acquisition by Process Insights, additional resources will propel Guided Wave into the next decade of innovation and industry leadership”, said Susan Foulk, President of Guided Wave.  “It’s exciting to join the Process Insights team, and the team at Guided Wave looks forward to opening new pathways for growth as we continue to put our customers and their process analytical needs first”, Foulk added.

“Guided Wave is a natural fit for Process Insights.  We share many common customers, markets and applications.  This is an exciting opportunity for Process Insights to continue to expand our total differentiated solution offerings to our customers with the addition of Guided Wave’s premium NIR and UV-VIS technologies to our portfolio”, said Monte Hammouri, CEO of Process Insights.  “We have known Guided Wave, Susan and her team for many years through prior collaborations.  Bringing them into the Process Insights family takes our collaboration to that next level where we can leverage Process Insights’ global scale and operating footprints to further accelerate Guided Wave’s growth and innovation”, added Hammouri.

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